Alzheimer’s disease is a common neurological disorder that typically affects individuals over the age of 65. This prevalent condition is found in approximately one in ten people worldwide.
.. Current research has identified various factors contributing to the progression of Alzheimer’s disease, from its initial onset in the brain to its final stages, which include significant shrinkage of gray matter and overall brain volume loss.
Advertisement
Casio 150 Steps Office Calculator
In Alzheimer's disease, the main components responsible for its progression include amyloid beta and tau proteins. Amyloid beta, in particular, forms a sticky substance that aggregates to create plaques in the brain. Beta-amyloid is a protein fragment, and these aggregates appear to be toxic to neurons, disrupting cell-to-cell communication when they clump together.
In neuronal tubules, tangles and tau proteins coexist. According to the tau hypothesis, abnormalities in tau protein are indicative of impending disease. As the microtubules in the cell's cytoskeleton deteriorate, the photoreceptor transport system disintegrates, ultimately leading to cell destruction.
By damaging nerve cells and the associated neurons, this, in turn, creates various tangles and plaques that obstruct transmission between the synapses of the neurons. These tubular structures inhibit certain substances from functioning as memory-enhancing compounds.
Comments